Brittle bone disease is most known as osteogenesis imperfecta (OI). It usually inherited disorder that can causes bones to break easy due the low production of collagen. There are different types of Osteogenesis imperfecta disease. The last two types, Type V and Type VI have been recently identified, and most data refer to only four different Osteogenesis imperfecta types. The types of Osteogenesis imperfecta disease indicates the degree to which the condition may impact life. While some people are severely affected by Osteogenesis imperfecta disease, others are able to live a relatively normal life.
Osteogenesis imperfecta with low levels of collagen characterize Type I brittle bone disease. This type is the most occurring and the least severe. Bones are likely to break easy before the onset of puberty. And those with Type I are prone to scoliosis, most curvature of the spine, and sometimes need to wear a brace as teenagers to correct the curve.
Osteogenesis imperfecta with Type I brittle bone disease may have poor muscle tone, be subject to early loss of hearing, and sometimes with discoloration in the whites of their eyes. Joints with loosened, causing some lack of coordination, resulting in easier breakage.